<< Return to News

Your Custom Microbial Fermentation Roadmap

When you partner with MDG for your custom fermentation needs, you can be confident that our microbiologists and production experts are committed to delivering a final culture that fits your specifications. We follow our Trusted Process closely, fostering success for our customers. But what does that process look like? Read on to discover what our custom microbial fermentation process entails, from pilot scale to commercialization.

Part One: Rapid Scale-Up

When you begin the custom fermentation process with MDG, your Bacillus strain will go through a process development program. This stage typically takes about twelve weeks to complete. The process development steps are as follows:

  1. MDG receives your strain in our in-house labs.
  2. Our microbiologists streak your strain to ensure purity.
  3. An initial growth screen begins, during which our specialists test your Bacillus strain’s growth ability on a multitude of different media.
  4. Growth media is narrowed down to a few top choices, and additional testing is performed to find the optimal media for your strain.
  5. Once we’ve found the right growth media, we will grow your strain on a pilot scale, harvest and dry the culture, and send it to you for evaluation.

After you give your approval on the final culture sample, the second part of the custom fermentation process can begin!

 

Part Two: Large-Scale Fermentation and Commercialization

Signing a contract with us and getting a spot on our fermentation schedule are the next steps when commercializing your strains with MDG. Depending on the volume needed, our team may start with small tanks or your strains might be scheduled for our 5,000 or 10,000 liter tanks right away. Our production facilities adhere to Good Manufacturing Practices (GMP) and are FSMA-compliant and HACCP-certified, so you know we take the necessary steps to ensure the quality and purity of your strain at every step of the process.

Once a tank is complete, our specialists harvest the culture and dry it, using either our spray dryers or freeze dryers. The result is a pure Bacillus culture in the form of a high-quality powder, ready to be used in your products and formulations.

 

Our Promises

MDG’s custom fermentation process encapsulates all three of the promises we make to each of our partners. In the lab, our microbiologists utilize Real Science during process development, finding the right media for your strain and optimizing growth conditions. Our production specialists follow a Trusted Process to ferment, harvest, and dry your strain. Finally, we see Proven Success in the commercialization process, getting you to scale efficiently and economically.

Interested in partnering with us for your custom fermentation needs? Contact us today and see how we can help you meet your unique goals and grow your business.

MDG is the Bacillus solution that helps you scale and streamline without sacrificing product effectiveness.

Search Insights
Recently Posted Insights

The Changing Landscape of the Human Health Market in 2025

If you’re a probiotic supplier or manufacturer in the United States, you may be feeling uncertain about the state of the human health market. Unpredictable tariff adjustments and shifting regulatory guidelines on topics like self-affirmed GRAS status are just a couple...

MDG at SIMB 2025: Your Trusted Microbial Contract Manufacturer

Join us at the 2025 Society for Industrial Microbiology and Biotechnology (SIMB) Annual Meeting! We’re exhibiting July 27–30 at the Hyatt Regency in San Francisco. Visit us at Booth #20 to speak with an expert in person and learn more about our capabilities for...

How to Help Your Wastewater Customers Prepare for Winter

The changing of the seasons can have a pronounced effect on wastewater systems, particularly when the weather gets cold. Lower temperatures correspond to a decrease in microbial activity, which slows the treatment process. If you’re looking for a solution for your...

Bacillus: The Smarter Solution for RV Sewage System Treatment

Summer is here, which means your customers might be bringing out their RVs for the first trip of the season. However, even on a carefree camping adventure, RVs need to be maintained, particularly their sewage systems. If you’re looking to add an RV tank treatment to...

Choose Bacillus for Septic System Maintenance

According to the EPA, over 20% of US homes rely on septic systems to treat their wastewater.1 When these systems are not properly maintained, multiple issues can arise, such as backups, odors, and flooding. To offer your customers reliable septic system maintenance...

A Distributor’s Guide to Improving Water Quality

Water quality is crucial for wastewater treatment facility operators to maintain—not only to meet compliance standards for their effluent, but also to keep their systems running smoothly. As experts in helping you monitor and improve this key metric at your customers’...

Transform Your Probiotic Products with BoostBac™

Our mission to Feed, Clean, Save the World focuses on improving human health and diving deep into research and development of Bacillus-based probiotic ingredients. We recently released our new probiotic product, BoostBac™, which positively affects the gut microbiome...

Related News