In the large-scale liquid bacterial fermentation world, there are two primary ways to grow bacteria: as individual strains or in combination with others. Here at Microbial Discovery Group, we grow one strain at a time as it has served us well over the past decade.
Truth be told, if I could find a way to grow multiple strains in one batch that was produced through a consistent process, resulted high yield and a uniformity in strain ratio,
Microbial Discovery Group (MDG) is growing in many ways! We began making plans to expand and increase custom fermentation capacity as we realized the potential for growth. To do so, we needed to relocate office and laboratory space from our original Franklin facility to an 80,000 ft² facility located in Oak Creek. MDG Oak Creek now houses three laboratories, office space, spray drying and additional blending capabilities, packaging, and
Typically, one of the first questions a contract fermentation customer will ask us is how quickly we can get them to economical commercial production. From our years of experience, we commonly find that if the customer can get 2 Billion CFU/ml (2B) in a standard media such as Trypticase Soy Broth (TSB) or Nutrient Broth (NB), we tend to be able to get them to commercial production in 8-12 weeks.
However, if the customer is in the 107 or 108
Throughout a facility tour at MDG you’ll walk past different sizes of the same equipment, one example, specifically of interest to many plant companies, is the 6-foot pilot spray dryer that stares up at a 34-foot electric production spray dryer. Flexibility in spray drying equipment size offers two intentional benefits: affordable trials and high-yield spore production.
What is Spray Drying?
At MDG, we make Bacillus cultures and products for a range of industries, including food. When it comes to serving our customers in this industry, specifically those manufacturing probiotics for human gut health, they often ask how we keep their cultures separate from those in the other markets that we serve.
To keep food ingredients safe from cross-contamination, we leverage a dedicated room and equipment for food ingredients and process
Well, ok, that’s not exactly how the saying goes, but this modified version seems fitting. Recently, MDG received its third centrifuge to match its three fermentors already in operation. This R2D2 looking device might sound boring, but it’s an essential piece of our custom fermentation arsenal.
So, why is having a third centrifuge so important? Simply put, improved production. The centrifuge spins the liquid from a
Not too long ago, a biofertilizer customer came to me frantically and explained, “I need to grow 7 strains of Bacillus in 3 weeks because it’s planting season and I can’t miss this year’s season.” I felt sorry for him, yet I had no choice but to say: “I’m sorry, but we cannot help you. Your timelines just aren’t realistic.” This exact interaction has happened more times than I care to remember. Trust me, I understand how big
As a follow up to the article “The Key Drivers Behind MDG’s Current Expansion,” I’d like to take this opportunity to talk more extensively about the expanding Bacillus market. Previously, I eluded that many of the current market opportunities were due to the increased demand across multiple industries. In particular, the following four main areas are what prompted Microbial Discovery Group’s (MDG) fermentation expansion:
Part of what is driving Microbial Discovery Group’s (MDG) current expansion is our desire to produce 50+ strains. Why do we want to be a Bacillus company that produces 50+ strains? Essentially: to offer the best service and products for our customers. Below are the three main reasons why our drive to produce 50+ strains is fueling our expansion.
MDG’s belief in multi-strain product offerings
The current Bacillus strain
It is an exciting day signing a multi-year fermentation contract! After the ink dries and celebrations conclude, I’ve learned it’s time to quickly review both redundancy and contingency plans for worst case scenarios. This is how we can guarantee on-time delivery.
During the planning of our current expansion, I was reminded again of the importance of redundancy in safeguarding against setbacks. I had received a call from another