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    [post_content] => Throughout a facility tour at MDG you’ll walk past different sizes of the same equipment, one example, specifically of interest to many plant companies, is the 6-foot pilot spray dryer that stares up at a 34-foot electric production spray dryer. Flexibility in spray drying equipment size offers two intentional benefits: affordable trials and high-yield spore production.   
What is Spray Drying?
[caption id="attachment_7069" align="alignright" width="151"] MDG's Pilot Spray Dryer[/caption]

Spray drying is used in markets such as custom fermentation, plant health, animal agriculture, wastewater, I&I, aquaculture, human probiotics, landfill, and bioremediation. This process involves drying liquid droplets into a fine powder. A nozzle that turns a stream

of liquid into a fine mist allows for droplets ranging in micron sizes to be achieved and produce fine particles as the water droplets dry. Fine particle sizes are required for applying product through in field spraying applications making it a popular drying method for agriculture products.  

Affordable Trials 

Field trials are a common step in bringing a new strain or product to market. Field trials require a small amount of high-quality product and bringing a product to market requires high amounts of high-quality product. While that may seem like stating the obvious, few manufacturers are set-up to execute on it.  

To keep field trials affordable, MDG runs products for field trials through the pilot spray dryer due to quantity of product grown from small fermentation batches. The pilot spray dryer allows for a faster turn-around and less cost to our partners compared to the alternative production dryer.  
Delivering the Highest Yield  
Every strain of bacteria is different. To produce the highest yield, we need to understand the optimal conditions to grow the strain, and the optimal conditions for drying. Downstream production should not be overlooked when discussing strain optimization. At MDG, we gain information from the pilot dryer before moving to the production dryer to optimize spray drying processes for the 5,000 and 10,000-liter fermentation batches. And soon, 50,000-liter fermentation batches.   

Whether we’re manufacturing product for a field-trial or a full production run, we’re in the interest of reducing costs, producing quality yields, and getting you product faster. The equipment investments that may seem small are proving to make the biggest difference.

Contact Us to discuss your upcoming trials or spray drying questions. 
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Custom Fermentation

Categories:

Two Big Reasons You Need Our Small Spray Dryer

MDG
April 20, 2022

Throughout a facility tour at MDG you’ll walk past different sizes of the same equipment, one example, specifically of interest to many plant companies, is the 6-foot pilot spray dryer that stares up at a 34-foot electric production spray dryer. Flexibility in spray drying equipment size offers two intentional benefits: affordable trials and high-yield spore production. What is Spray Drying? [caption id="attachment_7069"

-READ MORE-

2B or Not 2B? Success Criteria for Economical Bacillus Scale-Up

Mike King
January 20, 2021

Typically, one of the first questions a contract fermentation customer will ask us is how quickly we can get them to economical commercial production. From our years of experience, we commonly find that if the customer can get 2 Billion CFU/ml (2B) in a standard media such as Trypticase Soy Broth (TSB) or Nutrient Broth (NB), we tend to be able to get them to commercial production in 8-12 weeks. However, if the customer is in the 107 or 108

-READ MORE-

Processing Probiotic Cultures

MDG
June 16, 2020

At MDG, we make Bacillus cultures and products for a range of industries, including food. When it comes to serving our customers in this industry, specifically those manufacturing probiotics for human gut health, they often ask how we keep their cultures separate from those in the other markets that we serve. To keep food ingredients safe from cross-contamination, we leverage a dedicated room and equipment for food ingredients and process

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Good Things Always Happen in 3’s

MDG
April 21, 2020

Well, ok, that’s not exactly how the saying goes, but this modified version seems fitting. Recently, MDG received its third centrifuge to match its three fermentors already in operation. This R2D2 looking device might sound boring, but it’s an essential piece of our custom fermentation arsenal. So, why is having a third centrifuge so important? Simply put, improved production. The centrifuge spins the liquid from a

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Planting the Seed: Start with Your Fermentation Manufacturer Early

Mike King

Not too long ago, a biofertilizer customer came to me frantically and explained, “I need to grow 7 strains of Bacillus in 3 weeks because it’s planting season and I can’t miss this year’s season.” I felt sorry for him, yet I had no choice but to say: “I’m sorry, but we cannot help you. Your timelines just aren’t realistic.” This exact interaction has happened more times than I care to remember. Trust me, I understand how big

-READ MORE-

Supplying Quality: One Strain at a Time

Mike King
June 13, 2018

In the large-scale liquid bacterial fermentation world, there are two primary ways to grow bacteria: as individual strains or in combination with others. Here at Microbial Discovery Group, we grow one strain at a time as it has served us well over the past decade. Truth be told, if I could find a way to grow multiple strains in one batch that was produced through a consistent process, resulted high yield and a uniformity in strain ratio,

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The Expanding Bacillus Market

Mike King
May 16, 2018

As a follow up to the article “The Key Drivers Behind MDG’s Current Expansion,” I’d like to take this opportunity to talk more extensively about the expanding Bacillus market. Previously, I eluded that many of the current market opportunities were due to the increased demand across multiple industries. In particular, the following four main areas are what prompted Microbial Discovery Group’s (MDG) fermentation expansion:

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50+ Strains: Why We Supply

Mike King
May 4, 2018

Part of what is driving Microbial Discovery Group’s (MDG) current expansion is our desire to produce 50+ strains. Why do we want to be a Bacillus company that produces 50+ strains? Essentially: to offer the best service and products for our customers. Below are the three main reasons why our drive to produce 50+ strains is fueling our expansion. MDG’s belief in multi-strain product offerings The current Bacillus strain

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The Benefits of Fermentation Redundancy

Mike King
April 18, 2018

It is an exciting day signing a multi-year fermentation contract! After the ink dries and celebrations conclude, I’ve learned it’s time to quickly review both redundancy and contingency plans for worst case scenarios. This is how we can guarantee on-time delivery. During the planning of our current expansion, I was reminded again of the importance of redundancy in safeguarding against setbacks. I had received a call from another

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The Key Drivers Behind MDG’s Current Expansion

Mike King
April 13, 2018

I was recently asked the WHY behind our current expansion. When I started to break it down, there were 4 key drivers that went into the new MDG facility design: Capacity expansion Reliability via redundancy Production of 50+ strains The expanding Bacillus market Capacity expansion. This is the no-brainer for expanding. MDG was reaching 75% of our capacity, so we either had to expand or recognize there would be a future cap

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