Leaky gut is an issue often caused by inflammation of intestinal tissue cells. Sometimes, complications from this problem, commonly referred to as leaky gut syndrome, can lead to even more inflammation throughout the body, creating a negative cycle and potentially leading to a host of adverse health outcomes. In order to address these issues and improve your customers’ overall health, it’s essential to understand the link between inflammation and leaky gut. Luckily, probiotics with anti-inflammatory properties could offer a great solution—here’s how.
What is leaky gut?
Leaky gut refers to increased permeability of the intestinal lining. This lining is comprised of intestinal tissue cells and acts as a barrier between the gut and the rest of the body, allowing nutrients and other beneficial material to pass into the bloodstream while preventing the escape of undesirable bacteria, food particles, and toxins. However, if these cells become inflamed, intestinal permeability increases, reducing the lining’s ability to prevent potentially harmful substances from entering the bloodstream. As these substances leak out, they trigger a greater immune response, leading to increased, sustained inflammation.1,2
How are leaky gut and inflammation connected?
These two issues are closely tied: Leaky gut is caused by intestinal inflammation, and the resulting flow of unwanted bacteria and other material into the bloodstream leads to additional systemic inflammation. This is typically called leaky gut syndrome. Prolonged inflammation of the immune system can lead to a multitude of unpleasant health outcomes, including general digestive problems, increased susceptibility to allergens, cardiovascular issues, and other immune-related difficulties. One study even suggests that leaky gut could give rise to increased musculoskeletal pain because of its connection to systemic inflammation.2, 3
The Power of Probiotics
If your customers are seeking ways to address the problems that arise from leaky gut and systemic inflammation, probiotics can be an effective solution, particularly ingredients with anti-inflammatory properties. By improving the gut microbiome, probiotics positively impact the strength and integrity of the intestinal lining. This helps protect against leaky gut, which can subsequently decrease sustained immune system inflammation and its various adverse effects.1,2
MDG: Your Partner in Human Health Innovation
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MDG is the probiotic provider that helps you differentiate faster without the added risk of investing your own resources in the development process.
References
- Aleman, R. S., Moncada, M., & Aryana, K. J. (2023). Leaky gut and the ingredients that help treat it: A review. Molecules, 28(2), 619. https://doi.org/10.3390/molecules28020619
- Di Vincenzo, F., Del Gaudio, A., Petito, V., Lopetuso, L. R., & Scaldaferri, F. (2024). Gut microbiota, intestinal permeability, and systemic inflammation: A narrative review. Internal and Emergency Medicine, 19, 275–293. https://doi.org/10.1007/s11739-023-03374-w
- Álvarez-Herms, J., González, A., Corbi, F., Odriozola, I., & Odriozola, A. (2023). Possible relationship between the gut leaky syndrome and musculoskeletal injuries: The important role of gut microbiota as indirect modulator. AIMS Public Health, 10(3), 710–738. https://doi.org/10.3934/publichealth.2023049
