MDG News and Updates

Scaling up your microbial strain for commercial purposes is a highly complex process, and without the proper guidance, it can be hard to get it right. As your trusted CMO for custom microbial fermentation, we work with you to achieve your unique goals and drive your business forward. To help you get started, we asked our experts for their top tips to achieve success with microbial scale-up. Here’s what they shared: Begin with the end in mind. Each step of the custom microbial manufacturing process builds on the one before it. This is why we say you should “begin with the end in mind”—in other words, start with a clear vision of your final goal so you can select the proper upstream steps to get you there. To do this, ask yourself some basic questions: Will you need your final product in a powder or liquid form? If you need a powder, how should it be dried? How does your product need to be blended, packaged, and shipped? Once you ask the questions, the next step is finding answers. Let’s say we’ve just completed the fermentation step, and we now have spore slurry that you need dried. While this may […]

In 2025, MDG’s human health expert walked the expo floor at SupplySide Global in Las Vegas, connecting in person with other industry professionals and sharing MDG’s trusted expertise in probiotics. Sharing Our Expertise and Growing New Partnerships SupplySide Global is “the leading B2B trade show and conference for the supplement, food and beverage industries”, bringing together probiotic professionals from around the world to share new ideas, insights, and innovations. Attending these types of events helps us stay plugged into the marketplace so we can better serve our current and future customers. With MDG as your probiotic ingredient supplier, you can differentiate your products faster without the added risk of investing your own resources in the development process. Our expertise in Bacillus and strong emphasis on collaborative partnerships allow you to drive your business forward with confidence. Set Up a Meeting Missed us at SupplySide Global 2025? We’d love to see you at the next show we attend! To make sure you don’t miss an announcement, and to keep up with everything we’re doing in the human health market, sign up for our newsletter today.

As a trusted provider of Bacillus-based solutions, we are passionate about continuous innovation to better serve our partners. After years of planning and hard work, we are thrilled to share that we celebrated the grand opening of our third production facility with a ribbon cutting ceremony on Wednesday, September 3, 2025! Our newest 117,000-square-foot facility is located at 3403 W. Oakwood Road in Franklin and provides us with the necessary capacity to further our fermentation and lyophilization capabilities, all while supporting our vision to Feed, Clean, Save the World. Including our two other production locations, the new space brings us to a total of 55,000 liters of fermentation capacity. The ribbon cutting was attended by MDG leadership as well as the partners who’ve supported us along the way, including Milwaukee 7, the Wisconsin Economic Development Corporation, the City of Franklin, BioForward, and our parent company, United Animal Health. We are grateful to our partners for believing in our vision and providing us with the necessary resources to make this expansion project a success! To learn more about our evolving capabilities and explore how you can become a part of our ongoing journey, contact us today. MDG is the Bacillus solution […]

In 2025, MDG exhibited at the Recent Advances in Fermentation Technology (RAFT) Conference in Myrtle Beach, SC! We shared exciting details about our newest production facility and spoke with plenty of potential clients about our fermentation capabilities. About the Event RAFT brings together professionals from around the world to share new innovations and developments in the field of microbial fermentation. The RAFT program chairs say that the conference provides opportunities to learn about a wide variety of fermentation-related topics like “strain engineering, scaling up and down, digitalization, modeling, innovative [fermentor] designs and fermentation modes, and the integration of upstream and downstream processes”. Additionally, RAFT offers a chance for attendees to network and connect with potential vendors/service providers for their fermentation needs. Our Impact at RAFT 2025 On the exhibition floor, we showcased details about our expanded capabilities, made possible by the opening of our third production facility. With 55,000 liters of fermentation capacity, we are able to better serve both current and potential customers, applying Real Science to a Trusted Process that yields Proven Success with custom microbial fermentation and growth. Wondering where we’ll be next? Sign up for our newsletter so you don’t miss the next show announcement! In […]

Without the right support, launching and selling your biological wastewater treatment products can be a difficult task. Luckily, when you partner with MDG, you receive the necessary assistance and more through our Biotifx® Platform. Created specifically for value-add businesses in the wastewater industry, the Biotifx® Platform helps you harness the power of bioaugmentation so your team can start selling fast and at a high return. Through Products, Programs, and People, our experts give you the training and tools you need to succeed in the marketplace. Take a look at how each aspect of our platform propels your business forward: Products All Biotifx® wastewater products go through a rigorous research and development process. Our microbiologists pull from our expansive library to find Bacillus strains that will help you address specific, high-value treatment challenges like: Fats, oils, and grease (FOG) Sludge Hydrogen sulfide (H2S) and odors Water quality metrics Biotifx® products include a blend of micronutrients and biostimulants to heighten the strains’ performance. Our unique offerings are also available in a variety of delivery formats: liquids, powders, tablets, and more. Backed by our high-quality Bacillus-based products, you can drive your own business by offering your customers microbial solutions that are: Effective and […]

Healthy aging is an essential element of wellness for many consumers—in fact, in a NutraIngredients survey, 50% of people ranked healthy aging as an important goal. Unfortunately, there are a multitude of factors that may impede the healthy aging process. Recent research has shown there is a link between aging and inflammation, which some are calling “inflammaging”. Inflammaging refers to the low-grade inflammation that naturally occurs throughout the body as we get older, often due to changes in the gut microbiome. However, supplementation of anti-inflammatory probiotics could be a way to help ease the effects of inflammaging. Here’s what you need to know.1 The Connection Between Aging and the Gut Microbiome The human gut microbiome is complex, comprised of thousands of bacterial species. This diversity is key to keeping it healthy. However, as we age, gut microbiome diversity tends to diminish, particularly the populations of beneficial organisms that help maintain gut health. A decreasing population of good gut bacteria could lead to higher susceptibility to issues like leaky gut; this, in turn, could increase the low-grade inflammation that is a hallmark of inflammaging.2,3 Because of the relationship between aging and inflammation, the two create a negative cycle. Age-related decline of […]

Business owners know the importance of maintaining a clean restroom in their facilities. However, due to the nature of the room’s use, unpleasant smells are common. As a distributor or manufacturer of cleaning products, you want to offer your customers a cost-effective option that delivers long-lasting results. At MDG, we have the clear solution: Bacillus-based ingredients. How does Bacillus work for restroom cleaning? Bacillus bacteria are microscopic organisms that are particularly good at degrading odor-causing compounds found in bathrooms, such as ammonia or uric acid. One way Bacillus do this is by releasing enzymes that break these substances down into smaller pieces, making them easier to digest, both for Bacillus and for the other native beneficial bacteria in the environment. The digestion process removes odorous compounds from the area being cleaned, leading to fewer unpleasant smells. Additionally, as living organisms, Bacillus keep growing and multiplying after application. This means that odor reduction continues beyond the initial clean, giving your customers long-lasting restroom freshness. While chemical cleaners are popular, some can be abrasive. They also don’t typically penetrate the porous surfaces bathrooms often contain, which is where odor-causing compounds can hide. Bacillus, on the other hand, is able to reach the […]

2025 marked MDG’s third year attending and exhibiting at WEFTEC, the largest annual water quality event in North America! About the Event WEFTEC is an annual technical exhibition and conference focusing on the water industry, organized by the Water Environment Federation. During the show, attendees have plenty of opportunities to network, attend educational sessions, and discover new developments in the water sector. Our Impact at WEFTEC As leaders in biological wastewater treatment solutions, we see WEFTEC as the perfect place to share those solutions with a global audience. For our third year of exhibiting, we placed emphasis on the innovative, strategic approach we offer our distribution partners. We help our customers achieve measurable, repeatable success with bioaugmentation through our expert people, high-quality products, and cutting-edge programs. Stay Up to Date with Us We’d love to see you at the next show we attend! Sign up for our newsletter today so you don’t miss any announcements about where we’ll be next. MDG is the Bacillus solution that helps you scale and streamline without sacrificing product effectiveness.

If you’re a probiotic supplier or manufacturer in the United States, you may be feeling uncertain about the state of the human health market. Unpredictable tariff adjustments and shifting regulatory guidelines on topics like self-affirmed GRAS status are just a couple of the challenges affecting U.S.-based probiotic companies today. While conditions are always subject to change, it’s useful to have a baseline awareness of current market happenings so you’re prepared to navigate the road ahead—here’s what you need to know. Potential Elimination of Self-Affirmed GRAS Status If you’re not already familiar, there are currently two pathways to GRAS (generally recognized as safe) status for probiotic ingredients: self-affirmation and FDA review. If a company’s ingredients have self-affirmed GRAS status, the ingredients have been reviewed by internal experts, but the FDA has not been notified of their use in food, beverage, or probiotic/supplement products. An FDA-reviewed GRAS affirmation, on the other hand, occurs if the FDA is alerted via a GRAS notice and subsequently approves the ingredient.1 In early March 2025, the Department of Health and Human Services (HHS) released a statement sharing Secretary Robert F. Kennedy Jr.’s directive for the organization to “enhance the FDA’s oversight of ingredients considered to be […]

Leaky gut is an issue often caused by inflammation of intestinal tissue cells. Sometimes, complications from this problem, commonly referred to as leaky gut syndrome, can lead to even more inflammation throughout the body, creating a negative cycle and potentially leading to a host of adverse health outcomes. In order to address these issues and improve your customers’ overall health, it’s essential to understand the link between inflammation and leaky gut. Luckily, probiotics with anti-inflammatory properties could offer a great solution—here’s how. What is leaky gut? Leaky gut refers to increased permeability of the intestinal lining. This lining is comprised of intestinal tissue cells and acts as a barrier between the gut and the rest of the body, allowing nutrients and other beneficial material to pass into the bloodstream while preventing the escape of undesirable bacteria, food particles, and toxins. However, if these cells become inflamed, intestinal permeability increases, reducing the lining’s ability to prevent potentially harmful substances from entering the bloodstream. As these substances leak out, they trigger a greater immune response, leading to increased, sustained inflammation.1,2 How are leaky gut and inflammation connected? These two issues are closely tied: Leaky gut is caused by intestinal inflammation, and the […]